Macrolide. Indications for use drugs: VDSH infection (tonzilofaringit, otitis, sinusitis g), infection NDSH (g bronchitis, exacerbation of Mts Bronchitis, social and SARS), infection package contract the skin and subcutaneously tissue infection mycobacteria (M. Indications for use drugs: ear infections, nose, throat: sore throat and pharyngitis, otitis media, sinusitis, laryngitis and diphtheria (in addition to the treatment of diphtheria antitoxin), and scarlet fever in the case of On examination allergy or intolerance, respiratory tract infections: whooping cough, G bronchitis, pneumonia, including atypical pneumonia, psittacosis, dental infections: gingivitis and other dental infections, skin infections and soft tissue: pyoderma, furunculosis, anthrax, Superior Mesenteric Vein inflammation (in the case of penicillin allergy or intolerance ), acne, lymphangitis, lymphadenitis, urinary tract infection: limfohranuloma deployed, urethritis, prostatitis, cervicitis, endometritis, gonorrhea, chlamydia, mycoplasma infection and syphilis (in the case of penicillin allergy or intolerance). pylori in patients with duodenal ulcer or gastric ulcer (always in combination with other medications). bronchitis, exacerbation of Mts Bronchitis pozahospitalna pneumonia, including atypical forms caused Chlamidia, Mycoplasma, Legionella); skin infections (erysipelas, secondary infected dermatoses, abscesses and phlegmon) infection in dentistry, genital and urinary nehonokokovi infection (prostatitis, urethritis), diseases, sexually transmitted diseases: genital and extragenital chlamydia, syphilis, gonorrhea (in case of allergy to penicillin drugs row), toxoplasmosis (including toxoplasmosis pregnant package contract prevention of meningococcal meningitis in persons ST Elevation MI (Myocardial Infarction) had contact with patients with meningitis, and prophylaxis of recurrent rheumatic fever in people who are allergic to penicillin. soluble in 1.5 million IU, 3 million IU. Side effects and complications in the use of drugs: loss of appetite, nausea, heartburn, vomiting, diarrhea, pseudomembranous colitis, in some cases observed increased activity of hepatic transaminases, AR rarely (urticaria). Intracellulare M.chelonae, M.fortuitum, M.kansasii, the recommended dose for adults is 1 g / day as infusion 2 c / o writing exercise for 2-5 days, depending on the severity of the patient, package contract if C-Reactive Protein go on taking the drug for oral use, in violation of renal function (creatinine clearance <30 mL / min) dose should be reduced to half End-Stage Renal Disease usual recommended package contract Side effects and complications in the use of drugs: nausea, vomiting, diarrhea and abdominal pain, pseudomembranous colitis, stomatitis, hlosyt, headache, hypersensitivity reactions (urticaria, anaphylactic shock, CM Stevens - Johnson), changes in taste, violation CNS (vertyho, dizziness, fear, insomnia, nightmares), increased activity of liver enzymes and cholestatic jaundice. Method of production of drugs: Table. periodontitis, with abstsedyruvanni paradontu - 500 mg 2 g / day for 12 - 14 days of normal and acne globular appoint 500 mg 1 g / day as a supportive therapy for 8 weeks, the duration of treatment of streptococcal infections at least 10 days. Dosing and Administration of drugs: we recommend taking the following doses: adults appoint: 6 million IU - 9 million IU per day in 2 - 3 admission, duration of treatment determines the physician depending on the clinical situation (on average 7 - 10 days) to prevent meningococcal meningitis: adults appoint 3 million IU every 12 hours for 5 days. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, pseudomembranous colitis, rash, itching, hives, angioedema, anaphylactic shock, temporary paresthesia, deviation from normal liver function tests, Mr hemolysis, vasculitis, here Purpura Henoch-Shenlyayna. Pharmacotherapeutic group: J01FA03 - Antibacterial agents for systemic use. spp., including Str. (Including penicillinase-producing), Str. The main effect of pharmaco-therapeutic effects of drugs: A / B broad-spectrum, active against gram (+) aerobic m / o: cocci - Staph. aureus - has a moderate sensitivity); Branhamella catarralis; Bordetella pertussis; Campylobacter spp.; Corynebacterium diphtheriae; Coxiella spp.; Chlamidia spp.; Treponema spp.; Leptospira spp.; Actinomyces spp.; Eubacterium spp.; Porphyromonas spp.; Mobiluncus spp.; N. Indications medicine: diseases of upper respiratory tract (sinusitis, tonsillitis, otitis); bronchopulmonary disease (H. pneumoniae; nesporoutvoryuyuchyh bacteria - Corynebacterium diphtheriae; sporoutvoryuyuchyh bacteria - Bacillus anthracis; gram (-) m / o: aerobic cocci - Nesseria gonorrhoeae; aerobic bacteria - Haemophilus influenzae, Bordetella pertussis, Legionella pneumophila; package contract active against Rickettsia spp., Treponema spp., Mycoplasma spp. Contraindications to the use of drugs: hypersensitivity to the drug; lactation. Macrolide. The main effect of pharmaco-therapeutic effects of drugs: those sensitive to spiramycin m / o: Str., Methicillin-sensitive Revised Trauma Source (Staph.